Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.9
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%
Top Medical Research Studies
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
Most Useful Reviews
9
Eliminated body odour
57 people found this helpful
These are the first vitamins I ordered for treating my autoimmune disorder. I initially chose them for hair and nails, but I noticed calming effects on my nerves. The odour from under my breast disappeared after I started taking them. My neck and back pains subsided, and I experienced increased vaginal moisture. I realised my diet was inadequate, but these vitamins were a revelation. I felt energised in the mornings and found waking up easier.
Read More
9
Supports IVF plans
5 people found this helpful
This vitamin complex has lowered my homocysteine levels from 9.2 to 4.71, which is vital as we're planning IVF due to my autoimmune disorder. I highly recommend it for its effectiveness in supporting these health goals.
Read More
9
Improved symptoms
1 people found this helpful
Excellent B vitamins! They've notably improved my symptoms related to my autoimmune disorder. If I miss a dose, I quickly notice returns of neck pain and headaches. I’ve tested various brands, and this one stands out for its effectiveness in supporting my health.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eliminated body odour
57 people found this helpful
These are the first vitamins I ordered for treating my autoimmune disorder. I initially chose them for hair and nails, but I noticed calming effects on my nerves. The odour from under my breast disappeared after I started taking them. My neck and back pains subsided, and I experienced increased vaginal moisture. I realised my diet was inadequate, but these vitamins were a revelation. I felt energised in the mornings and found waking up easier.
Read More
9
Supports IVF plans
5 people found this helpful
This vitamin complex has lowered my homocysteine levels from 9.2 to 4.71, which is vital as we're planning IVF due to my autoimmune disorder. I highly recommend it for its effectiveness in supporting these health goals.
Read More
9
Improved symptoms
1 people found this helpful
Excellent B vitamins! They've notably improved my symptoms related to my autoimmune disorder. If I miss a dose, I quickly notice returns of neck pain and headaches. I’ve tested various brands, and this one stands out for its effectiveness in supporting my health.
Read More
9
Pain relief
I ordered this complex after my neurologist advised B vitamins for my autoimmune disorder. I was unable to find a suitable product locally. Happily, after a week of taking them, my pain diminished dramatically, and I’m keen to continue taking them for my health.
Read More
9
Noticeable improvement
I purchased from iHerb and am very pleased with my experience! The product is excellent, showing a marked improvement in my condition related to autoimmune disorder. The quality is high, and the price is reasonable. The fast shipping and superb customer service were bonuses. I will definitely order more.
Read More
Frequently Asked Questions
9
Pain relief
I ordered this complex after my neurologist advised B vitamins for my autoimmune disorder. I was unable to find a suitable product locally. Happily, after a week of taking them, my pain diminished dramatically, and I’m keen to continue taking them for my health.
9
Improved symptoms
1 people found this helpful
Excellent B vitamins! They've notably improved my symptoms related to my autoimmune disorder. If I miss a dose, I quickly notice returns of neck pain and headaches. I’ve tested various brands, and this one stands out for its effectiveness in supporting my health.
2
No noticeable effect
3 people found this helpful
Unfortunately, I did not notice any effect while using this product for my autoimmune disorder. I've since ordered Vitamin Code Garden of Life, which appears to be more effective as I see improvements with it.
9
Eliminated body odour
57 people found this helpful
These are the first vitamins I ordered for treating my autoimmune disorder. I initially chose them for hair and nails, but I noticed calming effects on my nerves. The odour from under my breast disappeared after I started taking them. My neck and back pains subsided, and I experienced increased vaginal moisture. I realised my diet was inadequate, but these vitamins were a revelation. I felt energised in the mornings and found waking up easier.
7.5
Nerve relief
19 people found this helpful
This vitamin B complex is superb for alleviating nerve issues, especially for those with diabetes or anyone experiencing sensations of numbness. The product quality is excellent, and it effectively supports relief from nerve-related problems linked to my autoimmune disorder.
7.5
Reduced fatigue
30 people found this helpful
This is one of the best products I’ve tried for my autoimmune disorder. After taking these vitamins, my chronic fatigue has improved significantly. I’ve been using naturally-derived vitamins for years, which can strain the liver, but this product works well for me without causing gastrointestinal issues. My mother's tooth inflammation also improved unexpectedly.
0
Allergic reaction
7 people found this helpful
I can't decide how many stars to give since I bought this due to misleading information online. I had an allergic reaction to just one capsule, developing a rash and experiencing discolouration of my urine. I've learned my lesson about self-prescribing for my autoimmune disorder—no more experiments.
7.5
Improved sleep quality
20 people found this helpful
I selected a complex of B vitamins while planning my pregnancy and initially had an adverse reaction with rashes due to my body's sensitivity to vitamins, which includes autoimmune disorder. Despite this, after introducing chelated magnesium, my acne began to lessen. I now sleep well and wake refreshed without an alarm. I'm content with my purchase, though I deduct a star because of my body's response.
9
Supports pregnancy planning
1 people found this helpful
After my doctor recommended increasing folate for my autoimmune disorder, I switched to Doctor's Best vitamins. They are better absorbed than standard folic acid, making them essential during pregnancy planning. I find them very effective for my needs.
7.5
Replenished deficiencies
1 people found this helpful
I ordered this complex for my mother, as instructed by her doctor to help with her autoimmune disorder. It effectively replenished her B vitamin deficiencies necessary for nerve signal conduction. Consultation with a doctor is crucial due to the high dosages.
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.
Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
8
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
8
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
References
- Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. doi:10.59556/japi.73.0892
- Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. doi:10.1186/s13256-025-05149-7
- Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. doi:10.1186/s13256-025-05095-4
- Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. doi:10.3390/nu16162665
- Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. doi:10.1136/bcr-2023-258703
